ea0025p237 | Pituitary | SFEBES2011
Smith Lorna
, Davies Elizabeth
, Gastaldello Annalisa
, Thompson Iain
, Perello Edward
, Korbonits Marta
, Campanella Michelangelo
, Fowkes Robert
Cannabinoids are known to exert effects throughout the endocrine system, including in the anterior pituitary. Whilst cannabinoid receptors (CB1 in particular) are expressed in numerous tissues, expression and function of an endocannabinoid system within specific anterior cell types has not been investigated. We have used well-characterised gonadotroph (LβT2 and αT3-1) and somatolactotroph (GH3) cell lines to establish the expression and functional role for cannabinoi...